I sold my old 2010 Dyna with 95,000km on the clock and replaced it with a 2015 BMW R1200GS in my hope it would be a "1 bike to rule them all"
Within a year I was missing riding a Harley. so I added a 2014 Fatbob About 18 months ago. The beemer has done nearly 80,000km in just under 3 years and the Harley 30,000km in 18 months.
Negatives
The Beemer ADV Bike is far superior in every way except soul, it has none and thats what I missed not riding a Harley. It does everything TOO easily.
It is also much more expensive to maintain (I service the Harley myself) and wears out some parts quite a bit faster than I'd like (Front disks after 40,000km)
Positives
Its ability to give sport bikes a run for their money in the twisties then hit a switch and go bush is invaluable. As is the removable luggage. I've done 1000km days on the beemer and felt fresh the next day whereas on the Dynas you do take a bit more of a beating. Heated grips and cruise control are also nice to haves. The quick shifter (up and down) is also magical.
But if I had to sell one tomorrow I'd part with the beemer in a heart beat.