I recently installed a set of S&S 551 EZ start cams (OH YEAH BABY!), gutted the cat, and did away with the HD SEPST tune and replaced it with the Revolution Performance EMS plug and play tuner. I chose ths system as I didn't want to mess around with PC's, maps, downloads, uploads, Vtuning or anything else associated with other add on tuners-- just plug and run.
You have to send the OEM ECM unit to RevPerf in the states for their massage (2 weeks door to door), so while that was happening I installed the cams (thanks again ANDO), gutted the cat, and did some cosmetic work.
The unit came back, I plugged it in, reset the throttle position (on-off on-off-on-off-on-off on-off with10 seconds between actions) then hit the start button. Engine ran a bit rough for a minute then started settling down as it started learning parameters. After around 100k's it should have learned everything it needs to do its stuff. Rode to work this am and it just gets better and better. Good thing is that annoying decel pop I had from new with the SEPST tuner has gone.
If I want to add headwork, change cams, bigger bore, etc I don't have to have it tuned again unless I went big bore/big comp/bigger cams at the one time. To re-tune it goes back to RevPerf for an adjustment FOC (+shipping I presume).
If your not looking to squeeze out the last bit of Torque/HP I can recommend one of these. It comes with 2 wideband O2 sensors/ the control unit/ all cabling and of course instructions. This is not just a simple "add fuel" tuner, but monitors the whole engine operating system parameters.
It's a little pricey but I figure it's offset by no dyno tuning required or personal lost time costs for frigging around with a PC-- which alone is worth gold to me.... I got mine from Jamie at FuelMoto in the states for $650 plus $49 shipping.
http://www.revperf.com/Precision/index.html
I see you sent this in last October, and got no responce. Hope I'm not to late. Anyway , thinking about the RP Precision EMS. If you get this message could you give an update on your experience with this tuner. My ride is a 2009 Electra Glide, so the o2 sensors will fit this tuner. I am tossing up this tuner or the Cobra Power Pro . Thanks Mark